🩸 Pediatric Neurology · Apollomedics Lucknow

Pediatric Stroke & Moyamoya Disease

Specialist diagnosis and management — Lucknow, Uttar Pradesh

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बच्चों में ब्रेन स्ट्रोक

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Overview

What is Pediatric Stroke & Moyamoya Disease?

Pediatric stroke — brain attack in children — is far less common than in adults but is an important cause of neurological disability in childhood. It affects approximately 2–8 per 100,000 children per year and occurs from birth through adolescence. Pediatric stroke includes both ischaemic stroke (blocked blood vessel) and haemorrhagic stroke (bleeding into the brain). Causes in children differ substantially from adults — sickle cell disease, congenital heart disease, infection, prothrombotic disorders, and vascular anomalies (including Moyamoya disease) are important paediatric-specific causes. Dr. Nishant Gopaal won 1st Prize at the National Pediatric Stroke Congress 2024 for research on Moyamoya disease — one of the rarest and most complex causes of childhood stroke.

Signs & Symptoms

Signs Parents Should Know

Acute focal weakness
Sudden weakness or paralysis of one side of the body, arm or leg — a medical emergency requiring immediate hospital attendance.
Speech difficulties
Sudden difficulty speaking, understanding speech, or slurred speech.
Facial droop
Asymmetry of the face, especially when smiling — one side appearing lower.
Sudden severe headache
The 'worst headache of life' — particularly in haemorrhagic stroke.
Vision changes
Sudden loss of vision in one or both eyes, double vision, visual field loss.
Seizures at onset
New seizures accompanying focal neurological deficits suggest stroke until proven otherwise.
Altered consciousness
Reduced responsiveness or loss of consciousness in haemorrhagic stroke.
When to Seek Help

When to See Dr. Nishant Gopaal

→Any sudden focal neurological deficit — EMERGENCY: go to A&E immediately
→Child with sickle cell disease and any neurological symptoms
→History of previous TIA or stroke-like episode
→Unexplained hemiplegia or weakness
→Moyamoya disease — specialist follow-up essential
⚠️ Emergency: If your child has a seizure lasting more than 5 minutes, sudden paralysis, or sudden loss of consciousness — call emergency services immediately or go to the nearest A&E.
At Apollomedics Lucknow

How We Diagnose

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Emergency MRI / MR Angiography
MRI with DWI sequences is the gold standard for acute stroke diagnosis. MR angiography images blood vessels to identify occlusion or stenosis.
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CT / CT Angiography
Used in acute haemorrhagic stroke — faster than MRI in emergency settings.
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Cardiac Evaluation
Echocardiogram and ECG — congenital heart disease and cardiac arrhythmias are important stroke causes.
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Thrombophilia Screen
Blood tests for prothrombotic disorders (Factor V Leiden, protein C/S deficiency, antiphospholipid antibodies).
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Sickle Cell Screen
Haemoglobin electrophoresis — sickle cell disease is the most common cause of childhood stroke in India.
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DSA / Catheter Angiography
For suspected Moyamoya disease or vascular malformations — the gold standard vascular imaging.
Management

Treatment Approach

Acute management follows FAST (Face, Arms, Speech, Time) principles — immediate hospitalisation is essential. Secondary prevention depends on the underlying cause. Anti-platelet therapy (aspirin) for ischaemic stroke; anticoagulation for cardioembolic and prothrombotic causes; regular blood transfusion or hydroxyurea for sickle cell disease. Moyamoya disease requires neurosurgical revascularisation (EDAS/pial synangiosis) — Dr. Gopaal coordinates multidisciplinary management with neurosurgery for these complex cases. Rehabilitation — physiotherapy, speech therapy, occupational therapy — is essential to maximise recovery.

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Common Questions

Frequently Asked Questions

Can children have strokes?

Yes. Stroke occurs at all ages including in neonates and infants. Childhood stroke is rare but real and important — it is one of the top 10 causes of death in children and a significant cause of long-term disability.

What is Moyamoya disease?

Moyamoya is a rare progressive cerebrovascular disorder in which the main arteries at the base of the brain gradually narrow and block. Tiny abnormal vessels form to compensate, giving the characteristic 'puff of smoke' (moyamoya in Japanese) appearance on angiography. It presents with stroke, TIAs, or headache. Dr. Gopaal's award-winning research focused on characterising Moyamoya disease in Indian children.

Can children recover fully from stroke?

Children generally have better recovery potential than adults due to greater brain plasticity. However, recovery depends on the extent and location of injury, the underlying cause, and the intensity of rehabilitation. Many children make substantial recovery with intensive early therapy.

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Medically authored & reviewed by Dr. Nishant Gopaal Consultant Pediatric Neurologist & Head of Child Development Centre · Apollomedics Super Speciality Hospital, Lucknow
MD Pediatrics · Post-Doctoral Fellowship in Pediatric Neurology (FIPN) · Pediatric Epilepsy Training (BPNA, UK) · ORCID: 0000-0002-8408-535X
Last reviewed: 2026-09-27 · Based on international guidelines (ILAE, AAP, AAN, NICE, WHO)
References:
  1. Ferriero DM et al. Management of Stroke in Neonates and Children. Stroke. 2019.
  2. Roach ES et al. Management of Stroke in Infants and Children. Stroke. 2008.
  3. Gopaal N et al. Clinico-etiological profile of Pediatric Moyamoya Disease. 2nd National Pediatric Stroke Congress. 2024.
Related Conditions & Services
📍 Pediatric Epilepsy 📍 Neuroinfections 📍 Autoimmune Encephalitis
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